The Starkrial Valley is a neutral territory mentioned in Neverseen that the plague had spread to. Physic's usual gnomish apothecary, located in this valley, was closed for that reason when she attempted to visit it. A gnome, Mitya, once mentioned that the ogres blocked the river that had flowed into the valley, stopping its history of being lush and hearty.
The southern end is home to the Lake of Blood, and much of the foliage has withered there. The lake is highly acidic, and things that touch the surface often will not survive. A cave was also mentioned on the side, as it was where Lady Gisela was dragged. This cave was later revealed to be an ogre prison. Physic's apothecary is presumably on the other side, as it was first overrun when the plague had not reached the lake.